Drug Discovery And Development Of New Medicine - 1417 Words

Describe and discuss recent developments in drug discovery. As our society is evolving so is diseases many drugs that were previously effective to cure certain diseases are simply not as effective any more or on the other hand there isn’t sufficient medicine to battle the current new health problems that are arising with our evolving society for example obesity and a range of cardiovascular diseases. In addition many of the medicine available today either only treats the symptom or cures the disease with the addition of unwanted side effects. Hence, this is why drug discovery and development is vital. It is through drug discovery and development that new medicine is found. Currently a lot of effort is going into Binuclear metallohydrolases as a target in drug development. This is due to the fact this enzyme group has the potential to find solutions to health problems such as erectile dysfunctions, osteoporosis, cardiovascular dieses and also even become the seed in possible eradication of some antibiotic resistance. The main enzymes in the binuclear metallohydrolases group that are most vital us are purple acid phosphatases, metallo-ÃŽ ²-lactamases and arginases. The homologous feature in all these enzymes is the existence of two very nearly touching metal ions that hold the ability to attract water molecules that will then act as a nucleophile in a very particular hydrolytic reaction the importance of this is that it means that binuclear acids will have a powerful ionicShow MoreRelatedA Brief Note On Malaria And Its Effects On The Worlds Poorest1441 Words   |  6 Pagesor Medicine, diseases like malaria â€Å"have plagued humankind for a millennium and constitute a major global health problem. 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